DoesMC1Rgenotype convey information about melanoma risk beyond risk phenotypes?

Melanoma Epidemiology, Risk Factors, and Clinical Phenotypes

Information about Bank Risk

The volatility of its share price reflects the volatility of the market value of a bank’s assets. We present data for the volatilities of individual banks’ shares that are implied by the prices of options on the banks’ shares. We present evidence that implied volatilities (IV’s) better forecast actual, future volatilities of share prices than historical volatilities do. Banks’ IV’s are correlat...

Do dividends convey information about future earnings?

Yes. We find that dividend changes predict future unexpected earnings changes in each of the next four quarters. These earnings impacts are persistent, leading to higher than expected earnings levels for at least three years after the dividend change. These results are robust to various measures of expected earnings, including analyst forecasts and a flexible function of past earnings and retur...

Interactive effects of MC1R and OCA2 on melanoma risk phenotypes.

The relationships between MC1R gene variants and red hair, skin reflectance, degree of freckling and nevus count were investigated in 2331 adolescent twins, their sibs and parents in 645 twin families. Penetrance of each MC1R variant allele was consistent with an allelic model where effects were multiplicative for red hair but additive for skin reflectance. Of nine MC1R variant alleles assayed,...

'Hygienic' lymphocytes convey increased cancer risk.

Risk of developing inflammation-associated cancers has increased in industrialized countries during the past 30 years. One possible explanation is societal hygiene practices with use of antibiotics and Caesarian births that provide too few early life exposures of beneficial microbes. Building upon a 'hygiene hypothesis' model whereby prior microbial exposures lead to beneficial changes in CD4+ ...